The injectable contraceptives depot medroxyprogesterone acetate Nesstar Publisher The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin levels: a secondary study from the WHICH randomized clinical trial. Theinjectablecontraceptivesdepotmedroxyprogesteroneacetate Chanel Avenant Mandisa Singata-Madlik Alexis J. Bick Donita Africander Yusentha Balakrishna Karl-Heinz Storbeck Johnson Mosoko Moliki Sigcinile Dlamini Salndave Skosana Jenni Smit Mags Beksinska Ivana Beesham Ishen Seocharan Joanne Batting G Justus Hofmeyr Janet P. Hapgood Nesstar Publisher South Africa Testosterone.NSDstat 436 20 Nesstar 200801 ID 436 0 1 436 218.5 126.007 Site 436 0 ECRU 285 MRU 151 ITT_arm 436 0 DMPA-IM 217 NET-EN 219 PPD0&25W_arm 436 0 DMPA-IM 183 NET-EN 149 excluded non-study D0 or 25W 94 excluded not receive 6M injection 10 Age 436 0 18 39 24.966 4.709 Ethnicity 436 0 Colored 1 Other African tribe 4 Xhosa 293 Zulu 138 marital_D0 436 0 Married 12 Single 424 education_D0 436 0 Attended college or University 89 High school, complete 177 High school, not complete 164 Min school leaving grade 9/standard 7 6 income_D0 436 0 Employed 53 Self-employed 8 Unemployed 375 marital_25W 434 0 Married 12 Single 422 education_25W 434 0 Attended college or University 89 High school, complete 176 High school, not complete 163 Min school leaving grade 9/standard 7 6 income_25W 434 0 Employed 53 Self-employed 8 Unemployed 373 DMPA 317 0 Yes 317 NETEN 130 0 Yes 130 D0_SHBG 436 0 4 234 55.635 30.872 25W_SHBG 434 2 1 131 28.797 18.838 T_D0_Sbimp 436 0 0.086 16 0.104 1 0.156 1 0.173 2 0.177 1 0.180 1 0.184 1 0.187 2 0.191 1 0.194 2 0.198 1 0.201 1 0.205 3 0.208 3 0.211 1 0.215 1 0.218 1 0.222 2 0.225 3 0.229 2 0.232 1 0.236 1 0.243 1 0.246 4 0.250 1 0.253 2 0.257 1 0.260 3 0.264 2 0.270 4 0.277 2 0.281 1 0.284 1 0.288 4 0.291 1 0.295 1 0.298 1 0.302 2 0.305 3 0.312 3 0.322 1 0.326 2 0.329 3 0.333 5 0.336 2 0.340 2 0.343 1 0.347 1 0.350 4 0.354 4 0.357 1 0.361 2 0.364 2 0.368 4 0.371 2 0.374 6 0.378 3 0.381 3 0.388 2 0.392 3 0.399 2 0.402 1 0.406 3 0.409 3 0.413 2 0.416 3 0.420 1 0.423 3 0.426 3 0.430 2 0.440 1 0.444 1 0.447 1 0.451 2 0.454 1 0.458 1 0.461 1 0.468 3 0.472 1 0.475 1 0.478 1 0.482 2 0.485 3 0.489 5 0.503 2 0.506 1 0.510 1 0.513 2 0.517 2 0.524 1 0.527 4 0.530 2 0.537 1 0.541 6 0.544 2 0.551 6 0.555 2 0.558 4 0.562 2 0.565 4 0.569 2 0.572 2 0.576 4 0.579 1 0.586 3 0.589 1 0.596 1 0.600 1 0.603 1 0.607 2 0.610 1 0.614 2 0.617 1 0.621 2 0.624 2 0.634 1 0.638 1 0.648 3 0.652 3 0.655 1 0.662 2 0.666 2 0.669 2 0.673 1 0.676 1 0.680 2 0.683 7 0.686 1 0.690 1 0.693 2 0.704 2 0.711 1 0.714 2 0.718 3 0.725 2 0.732 1 0.735 2 0.739 3 0.745 1 0.749 1 0.752 1 0.756 2 0.759 3 0.763 1 0.770 1 0.773 1 0.780 1 0.784 1 0.787 2 0.797 2 0.801 1 0.804 3 0.808 2 0.811 1 0.815 2 0.818 1 0.825 1 0.829 1 0.836 3 0.846 1 0.853 1 0.856 2 0.860 1 0.867 1 0.870 2 0.888 2 0.891 2 0.895 1 0.898 2 0.905 3 0.908 1 0.915 1 0.933 1 0.936 1 0.947 2 0.960 1 0.964 1 0.967 1 0.974 1 0.985 2 0.999 1 1.002 1 1.005 1 1.016 2 1.019 2 1.030 1 1.033 1 1.037 1 1.044 2 1.047 1 1.054 1 1.057 1 1.061 1 1.078 1 1.082 2 1.089 1 1.092 1 1.123 1 1.134 1 1.137 1 1.151 1 1.158 1 1.162 1 1.165 1 1.182 2 1.186 1 1.189 2 1.196 1 1.203 1 1.210 1 1.227 2 1.234 1 1.293 1 1.307 1 1.338 1 1.352 1 1.363 1 1.401 1 1.425 1 1.453 1 1.487 1 1.508 1 1.512 1 1.553 1 1.564 1 1.598 3 1.633 1 1.761 1 1.799 1 1.831 1 1.893 1 1.952 2 1.973 1 2.080 1 2.094 1 2.302 1 2.361 1 2.420 1 2.680 1 2.788 1 2.968 1 4.344 1 na 3 T_25W_Sbimp 436 0 0.043 5 0.086 63 0.153 1 0.177 4 0.180 4 0.184 2 0.187 7 0.191 3 0.194 8 0.198 2 0.201 1 0.205 5 0.208 4 0.215 2 0.218 3 0.222 2 0.225 1 0.229 7 0.232 3 0.236 4 0.239 5 0.243 3 0.246 5 0.250 4 0.253 6 0.257 6 0.260 4 0.264 2 0.267 4 0.270 4 0.274 1 0.277 4 0.281 7 0.284 3 0.288 2 0.291 4 0.295 2 0.298 2 0.302 5 0.305 2 0.309 1 0.312 3 0.316 4 0.319 3 0.322 3 0.326 1 0.329 3 0.333 1 0.336 3 0.343 2 0.347 1 0.350 4 0.354 3 0.357 8 0.361 2 0.368 2 0.371 1 0.374 2 0.378 5 0.385 4 0.388 1 0.392 1 0.395 4 0.399 1 0.406 2 0.409 1 0.413 2 0.416 4 0.420 2 0.423 3 0.426 2 0.430 1 0.433 4 0.440 2 0.444 1 0.447 2 0.454 2 0.458 2 0.461 1 0.465 2 0.472 2 0.475 2 0.478 2 0.482 1 0.485 5 0.489 3 0.492 2 0.496 1 0.503 2 0.506 1 0.513 3 0.517 1 0.524 1 0.527 1 0.534 1 0.537 5 0.541 1 0.544 1 0.548 1 0.551 1 0.555 1 0.558 1 0.562 3 0.565 2 0.572 1 0.576 1 0.579 1 0.582 2 0.586 1 0.589 3 0.593 3 0.607 1 0.610 1 0.614 1 0.617 1 0.621 1 0.631 1 0.641 2 0.648 3 0.655 2 0.659 2 0.662 1 0.666 1 0.669 1 0.673 2 0.680 1 0.686 2 0.693 1 0.711 1 0.718 1 0.725 2 0.735 1 0.739 1 0.752 2 0.756 1 0.759 2 0.766 1 0.770 1 0.773 2 0.797 1 0.818 1 0.849 2 0.856 1 0.863 2 0.867 1 0.874 1 0.881 1 0.884 1 0.888 4 0.891 1 0.915 2 0.926 1 0.933 1 0.960 1 1.019 1 1.037 2 1.051 1 1.078 1 1.085 1 1.092 1 1.158 1 1.172 1 1.207 1 1.220 1 1.227 1 1.286 1 1.439 1 1.879 1 2.035 1 na 2 Free T_D0_Sbimp 436 0 0.000 22 0.001 39 0.002 44 0.003 33 0.004 41 0.005 17 0.006 23 0.007 19 0.008 23 0.009 15 0.010 10 0.011 11 0.012 13 0.013 9 0.014 12 0.015 12 0.016 3 0.017 8 0.018 7 0.019 6 0.020 3 0.021 2 0.022 4 0.023 4 0.024 1 0.025 1 0.026 2 0.027 4 0.029 3 0.030 2 0.033 2 0.034 1 0.035 5 0.038 1 0.039 1 0.040 3 0.041 3 0.045 1 0.046 1 0.047 1 0.053 1 0.056 1 0.057 1 0.064 1 0.066 1 0.069 1 0.070 1 0.072 2 0.073 2 0.074 2 0.081 1 0.116 1 0.117 1 0.136 1 0.166 1 0.194 1 0.238 1 0.609 1 na 3 Free T_25W_Sbimp 436 0 #DIV/0! 1 0.000 44 0.001 52 0.002 49 0.003 45 0.004 26 0.005 21 0.006 22 0.007 18 0.008 19 0.009 17 0.010 9 0.011 6 0.012 13 0.013 11 0.014 8 0.015 10 0.016 8 0.017 4 0.018 4 0.019 1 0.020 7 0.021 2 0.022 1 0.023 1 0.025 6 0.027 1 0.028 1 0.029 1 0.030 2 0.031 3 0.033 3 0.034 2 0.037 1 0.043 1 0.047 1 0.052 1 0.057 1 0.059 2 0.068 1 0.071 1 0.084 1 0.088 1 0.100 1 0.101 1 0.108 1 0.174 1 na 3