Effects of injectable contraception with depot medroxyprogesterone acetate or norethisterone enanthate on estradiol levels and menstrual, psychological and behavioral measures relevant to HIV risk: the WHICH randomized trial Nesstar Publisher Effects of injectable contraception with depot medroxyprogesterone acetate or norethisterone enanthate on estradiol levels and menstrual, psychological and behavioral measures relevant to HIV risk: the WHICH randomized trial EffectsOfInjectableContraceptive Mandisa Singata-Madliki Jenni Smit Mags Beksinska Yusentha Balakrishna Chanel Avenant Ivana Beesham Ishen Seocharan Joanne Batting Janet P. Hapgood G Justus Hofmeyr Nesstar Publisher South Africa WHICH_demo_estradiol_behaviour.NSDstat 972 25 Nesstar 200801 WHICH_daily_diary.NSDstat 427 25 Nesstar 200801 ID 972 0 1 520 258.679 150.821 site 972 0 ECRU 626 MRU 346 ITT_arm 972 0 DMPA 487 NET-EN 485 PP_arm 972 0 DMPA 485 NET-EN 487 visit_code 972 0 25 weeks 452 Baseline 520 age 972 0 18 39 24.844 4.706 ethnicity 972 0 Mixed race 2 Other African Tribe 8 Xhosa 647 Zulu 315 marital 972 0 Married 24 Single 948 education1 972 0 Attended college or University 203 High school, complete 398 High school, not complete 357 Min school leaving grade 9/standard 7 14 income 972 0 Employed 122 Self-employed 16 Unemployed 834 dmpa 972 0 No 266 Yes 706 neten 972 0 No 672 Yes 300 asex_score 970 2 3 70 4 5 5 132 6 90 7 58 8 100 9 171 10 83 11 49 12 28 13 28 14 27 15 89 16 20 17 7 18 9 19 2 20 1 22 1 Sysmiss 2 sexual_dysfunction 970 0 No 929 Yes 41 bdi_score 970 2 0 30 1.722 2.407 any_depression 970 0 No 965 Yes 5 feeling_sad 966 0 No 877 Unknown 2 Yes 87 no_mens 965 0 No 725 Yes 240 no_pain 725 0 Painful menstruation 77 Painless menstruation 648 no_sex 966 0 No 773 Yes 193 no_condom 773 0 No 660 Yes 113 desire 966 0 No 924 Unknown 3 Yes 39 hiv 972 0 Indeterminate 1 Negative 959 Not done 2 Positive 10 pregnant 966 0 No 925 Yes 41 estradiol 966 6 1 3670 205.699 293.657 ID 427 0 1 520 251.504 150.304 site 427 0 ECRU 283 MRU 144 ITT_arm 427 0 DMPA 210 NET-EN 217 PP_arm 427 0 DMPA 209 NET-EN 218 complete_obs 427 0 27 1 28 426 menstruating_days 427 0 0 28 1.255 2.935 no_mens 427 0 No 124 Yes 303 severe_pain 427 0 No 415 Yes 12 sex_days 427 0 0 28 5.288 5.104 steady_days 427 0 0 28 5.014 5.022 casual_days 427 0 0 379 1 23 2 11 3 4 4 2 5 2 6 1 7 4 8 1 nosex 427 0 No 327 Yes 100 condomless_days 427 0 0 25 3.068 4.3 condom_casual_total 427 0 0 396 1 17 2 5 3 2 4 3 5 1 6 2 7 1 condom_steady_total 427 0 0 230 1 48 2 34 3 28 4 17 5 14 6 9 7 10 8 9 9 7 10 5 11 3 12 4 13 1 14 2 15 2 16 2 19 2 nocondom 427 0 No 204 Yes 223 sex_mens_total 427 0 0 396 1 17 2 8 3 4 5 1 6 1 sex_during_mens_bin 427 0 No 396 Yes 31 condomless_sex_mens_total 427 0 0 411 1 11 2 1 3 2 5 1 6 1 condomless_sex_during_mens_bin 427 0 0 411 1 16 urge_days 427 0 0 28 6.393 7.33 no_affection_days 427 0 0 28 2.513 5.987 no_affection_bin 427 0 At least one day of no affection 137 None 290 sad_days 427 0 0 28 3.944 6.022 sad_bin 427 0 At least one day of feeling sad for no reason 262 None 165